Inflammation, ageing, and bone regeneration

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Inflammation, ageing, and bone regeneration

Summary Bone healing involves complex biological pathways and interactions among various cell types and microenvironments. Among them, the monocyte-macrophage-osteoclast line-age and the mesenchymal stem cell-osteoblast lineage are critical, in addition to an initial inflammatory microenvironment. These cellular interactions induce the necessary inflammatory milieu and provide the cells for bon...

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ژورنال

عنوان ژورنال: Journal of Orthopaedic Translation

سال: 2017

ISSN: 2214-031X

DOI: 10.1016/j.jot.2017.04.002